| Pair Name | Anacardic Acid, Fluorouracil | ||
| Phytochemical Name | Anacardic Acid (PubChem CID: 167551 ) | ||
| Anticancer drug Name | Fluorouracil (PubChem CID: 3385 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Anacardic Acid, Fluorouracil | |||
| Disease Info | [ICD-11: 2C10.Z] | Pancreatic cancer | Investigative | |
| Gene Regulation | Up-regulation | Expression | CHMP1A | hsa5119 |
| Up-regulation | Phosphorylation | TP53 | hsa7157 | |
| In Vitro Model | Capan-2 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0026 |
| BxPC-3 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0186 | |
| PANC-1 | Pancreatic ductal adenocarcinoma | Homo sapiens (Human) | CVCL_0480 | |
| Result | Our data suggests that Anacardic Acid might be a promising complementary supplement to slow the initiation or progression of pancreatic cancer. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway. BMC Complement Altern Med. 2018 Feb 20;18(1):71. doi: 10.1186/s12906-018-2139-3. | Click |
